University of Chicago :: Department of Pathology ::

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Jose Quintans, MD, PhD

Professor
Director, Medical Scientist Training Program
Master, Biological Sciences Collegiate Division

The University of Chicago
5841 S. Maryland Avenue, BSLC 300
Chicago, IL 60637-1470
Telephone: (773) 702-7964
Fax: (773) 702-225
qui4@uchicago.edu

Chmura SJ, Nodzenski E, Kharbanda S, Pandey P, Quintans J, Kufe DW, Weichselbaum RR. Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis. Mol Pharmacol. 2000 Apr;57(4):792-6.
Chmura SJ, Mauceri HJ, Advani S, Heimann R, Beckett MA, Nodzenski E, Quintans J, Kufe DW, Weichselbaum RR. Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation. Cancer Res. 1997 Oct 1;57(19):4340-7.

Wiesner DA, Kilkus JP, Gottschalk AR, Quintans J, Dawson G. Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL. J Biol Chem. 1997 Apr 11;272(15):9868-76.
Chmura SJ, Nodzenski E, Beckett MA, Kufe DW, Quintans J, Weichselbaum RR. Loss of ceramide production confers resistance to radiation-induced apoptosis. Cancer Res. 1997 Apr 1;57(7):1270-5.
Bergmann BM, Rechtschaffen A, Gilliland MA, Quintans J. Effect of extended sleep deprivation on tumor growth in rats. Am J Physiol. 1996 Nov;271(5 Pt 2):R1460-4.