University of Chicago :: Department of Pathology ::

Quick Links

Jonathan Miller, MD, PhD

Professor and Vice Chairman

Contact

Department of Pathology
The University of Chicago
5841 S. Maryland Avenue, MC 3083
Chicago IL 60637-1470
Phone: (773) 702-1878
Fax: (773) 834-8590
jlmiller@bsd.uchicago.edu

Research Interests

Study of the regulation of the platelet receptor for von Willebrand factor (glycoprotein Ib/IX/V complex), with long-term goal the development of anti-thrombotic agents based upon insights gained from study of the pathophysiology of platelet-type von Willebrand disease and the Bernard-Soulier disease syndromes. Molecular characterization of autoantibody development against the glycoprotein Ib/IX/V complex in ITP.

Selected Publications

Lotan T.L, Tefs K., Schuster V., Miller J. , Manaligod J., Filstead A., Yamada S.D., Krausz T. Inherited plasminogen deficiency presenting as ligneous vaginitis: A case report with molecular correlation and review of the literature. Human Pathology, 2007; 1569-75.
Genzen, J.R. and Miller, J.L. Presence of direct thrombin inhibitors can sffect the results and interpretation of lupus anticoagulant testing. Am J Clin Pathol., 2005, 124:586-593.
Doggett TA, Girdhar G, Lawshe A, Miller JL, Laurenzi IJ, Diamond SL, Diacovo TG. . Alterations in the intrinsic properties of the GPIbalpha-VWF tether bond define the kinetics of the platelet-type von Willebrand disease mutation, Gly233Val. Blood.2003; 120:152-160.
Mathur SC, Vajpayee N, Narsipur SS, Miller JL. Changes in platelet function following hemodialysis in patients with end-stage renal disease. Thromb Haem Suppl, July 2001.
Miller JL, Awasthi A, Lyle VA, Blystone SD, Gavalchin J. Detection of human anti-platelet antibodies using a fluorescence resonance energy transfer approach with heterologous cells. Thromb Haem Suppl, July 2001.
Chitale N, Miller JL. Complete inhibition of shear-induced platelet aggregation (SIPA) by HIb-2, a human anti-human platelet GPIb ScFv. Blood. 2001.

View all publications